Ribonucleotide reductases: essential enzymes for bacterial life
نویسندگان
چکیده
منابع مشابه
Ribonucleotide reductases: essential enzymes for bacterial life
Ribonucleotide reductase (RNR) is a key enzyme that mediates the synthesis of deoxyribonucleotides, the DNA precursors, for DNA synthesis in every living cell. This enzyme converts ribonucleotides to deoxyribonucleotides, the building blocks for DNA replication, and repair. Clearly, RNR enzymes have contributed to the appearance of genetic material that exists today, being essential for the evo...
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Ribonucleotide reductases [EC 1.17.4.] are a group of enzymes which critically contribute to the biosynthesis of deoxyribonucleotides (dNTPs), the monomeric precursors of DNA polymerization. By a radical reaction mechanism, they catalyze the reduction of the ribonucleotides, ADP, GDP, CDP, and UDP, mostly at the diphosphate level, to their deoxy conterparts dADP, dGDP, dCDP, and dUDP, respectiv...
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ژورنال
عنوان ژورنال: Frontiers in Cellular and Infection Microbiology
سال: 2014
ISSN: 2235-2988
DOI: 10.3389/fcimb.2014.00052